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Journal of Nutrition Research
An official journal of IAPEN India association

Article

Uses of Probiotics and Immunonutrition in Gastrointestinal Disorders – Recommendations and Practices
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Journal of Nutrition Research

DOI: 10.55289/jnutres/v12i1_23.29

Year: 2024, Volume: 12, Issue: 1, Pages: 8-14

Guideline

Uses of Probiotics and Immunonutrition in Gastrointestinal Disorders – Recommendations and Practices

S S Safeena Beevi​✉ 1 , Uwais Ashraf 2

1 Associate Professor, Aligarh Muslim University, Uttar Pradesh, India
2 Assistant Professor, JNMCH, Aligarh Muslim University, Uttar Pradesh, India
 
Corresponding author email: [email protected]

Received Date:24 November 2023, Accepted Date:07 March 2024, Published Date:07 June 2024

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Probiotics play a key role in restoring the normal gut microbiota and improves the gastrointestinal function. Generally, probiotics are pondered to be dietary factors which have an impact on the gut microbiota and to have a monitoring effect on the intestinal flora. The gut-liver axis has a pivotal role in the liver disease pathophysiology. Immunonutrition uses nutritional interventions to produce health-related effects beyond the primary nutrient value and regulate the neuroendocrine immunoinflammatory responses. Few studies are favouring the use of probiotics and immunonutrition in gastrointestinal disease. Still not much evidence-based guidelines pertaining to the uses of immunonutrition and probiotics are available. This article will provide an overview of the current practices and guidelines in the use of probiotics and immunonutrients in gastrointestinal diseases.

Keywords

Probiotics, Immunonutrition, Gut­liver axis, Gut microbiota, Sarcopenia

References

  1. Fao/Who. 2006.
  3. Koliwad SK, Kuo T, Shipp LE, Gray NE, Backhed F, So AYL, et al. Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism. Journal of Biological Chemistry. 2012;287(6):4394. doi: 10.1074/jbc.a109.025452
  4. Bellot P, Francés R, Such J. Pathological bacterial translocation in cirrhosis: pathophysiology, diagnosis and clinical implications. Liver International. 2013;33(1):31–39. doi: 10.1111/liv.12021
  5. Nitin J, Mithun S, PN R, Reddy DN. Liver Diseases: The Role of Gut Microbiota and Probiotics. Journal of Probiotics & Health. 2016;04(03):154–62. doi: 10.4172/2329-8901.1000154
  6. Hemarajata P, Versalovic J. Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation. Therapeutic Advances in Gastroenterology. 2013;6(1):39–51. doi: 10.1177/1756283x12459294
  7. Santoni M, Miccini F, Battelli N. Gut microbiota, immunity and pain. Immunology Letters. 2021;229:44–47. doi: 10.1016/j.imlet.2020.11.010
  8. Monteagudo-Mera A, Rastall RA, Gibson GR, Charalampopoulos D, Chatzifragkou A. Adhesion mechanisms mediated by probiotics and prebiotics and their potential impact on human health. Applied Microbiology and Biotechnology. 2019;103(16):6463–6472. doi: 10.1007/s00253-019-09978-7
  9. Bron PA, Kleerebezem M, Brummer RJ, Cani PD, Mercenier A, MacDonald TT, et al. Can probiotics modulate human disease by impacting intestinal barrier function? British Journal of Nutrition. 2017;117(1):93–107. doi: 10.1017/s0007114516004037
  10. Liu Q, Yu Z, Tian F, Zhao J, Zhang H, Zhai Q, et al. Surface components and metabolites of probiotics for regulation of intestinal epithelial barrier. Microbial Cell Factories. 2020;19(1):23. doi: 10.1186/s12934-020-1289-4
  11. Kumar Bajaj B, J.J. Claes I, Lebeer S. FUNCTIONAL MECHANISMS OF PROBIOTICS. Journal of microbiology, biotechnology and food sciences. 2015;4(4):321–327. doi: 10.15414/jmbfs.2015.4.4.321-327
  12. Ohland CL, MacNaughton WK. Probiotic bacteria and intestinal epithelial barrier function. American Journal of Physiology-Gastrointestinal and Liver Physiology. 2010;298(6):G807–G819. doi: 10.1152/ajpgi.00243.2009
  13. Mousavi Khaneghah A, Abhari K, Eş I, Soares MB, Oliveira RBA, Hosseini H, et al. Interactions between probiotics and pathogenic microorganisms in hosts and foods: A review. Trends in Food Science & Technology. 2020;95:205–218. doi: 10.1016/j.tifs.2019.11.022
  14. Iqbal Z, Ahmed S, Tabassum N, Bhattacharya R, Bose D. Role of probiotics in prevention and treatment of enteric infections: a comprehensive review. 3 Biotech. 2021;11(5):242. doi: 10.1007/s13205-021-02796-7
  15. La Fata G, Weber P, Mohajeri MH. Probiotics and the Gut Immune System: Indirect Regulation. Probiotics and Antimicrobial Proteins. 2018;10(1):11–21. doi: 10.1007/s12602-017-9322-6
  16. KANG HJ, IM SH. Probiotics as an Immune Modulator. Journal of Nutritional Science and Vitaminology. 2015;61(Supplement):S103–S105. doi: 10.3177/jnsv.61.s103
  17. Eslami M, Bahar A, Keikha M, Karbalaei M, Kobyliak NM, Yousefi B. Probiotics function and modulation of the immune system in allergic diseases. Allergologia et Immunopathologia. 2020;48(6):771–788. doi: 10.1016/j.aller.2020.04.005
  18. Guarner F, Khan AG, Garisch J, Eliakim R, Gangl A, Thomson A, et al. World Gastroenterology Organisation Global Guidelines. Journal of Clinical Gastroenterology. 2012;46(6):468–481. doi: 10.1097/mcg.0b013e3182549092
  20. Skokovic-Sunjic D. Available from: http://usprobioticguide.com/
  21. Ghoshal UC, Gwee K, Holtmann G, Li Y, Park SJ, Simadibrata M, et al. The role of the microbiome and the use of probiotics in gastrointestinal disorders in adults in the Asia‐Pacific region ‐ background and recommendations of a regional consensus meeting. Journal of Gastroenterology and Hepatology. 2018;33(1):57–69. doi: 10.1111/jgh.13840
  22. Sharma P, Sharma BC, Puri V, Sarin SK. An open-label randomized controlled trial of lactulose and probiotics in the treatment of minimal hepatic encephalopathy. European Journal of Gastroenterology & Hepatology. 2008;20(6):506–511. doi: 10.1097/meg.0b013e3282f3e6f5
  23. Xia X, Chen J, Xia J, Wang B, Liu H, Yang L, et al. Role of probiotics in the treatment of minimal hepatic encephalopathy in patients with HBV-induced liver cirrhosis. Journal of International Medical Research. 2018;46(9):3596–3604. doi: 10.1177/0300060518776064
  24. Beier JI, Arteel GE, McClain CJ. Advances in Alcoholic Liver Disease. Current Gastroenterology Reports. 2011;13(1):56–64. doi: 10.1007/s11894-010-0157-5
  26. Li Z, Yang S, Lin H, Huang J, Watkins PA, Moser AB, et al. Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. Hepatology. 2003;37(2):343–350. Available from: https://doi.org/10.1053/jhep.2003.50048
  27. Gao X, Zhu Y, Wen Y, Liu G, Wan C. Efficacy of probiotics in non‐alcoholic fatty liver disease in adult and children: A meta‐analysis of randomized controlled trials. Hepatology Research. 2016;46(12):1226–1233. doi: 10.1111/hepr.12671
  28. Beevi S S S, Pottakkat B. Nutritional Assessment and Clinical Determinants in Patients Awaiting Liver Transplant. Current Research in Nutrition and Food Science Journal. 2022;10(2):790–801. doi: 10.12944/crnfsj.10.2.31
  29. Safeena Beevi SS, Om Prakash Veragi W, Hasan. Assessment Techniques of Sarcopenia in Chronic Liver Disease. Medicon Medical Sciences. 2023;4(2):20–24.
  30. Beevi S S S, Pottakkat B, Narayanan S. Role of Probiotics and Gut microbiota in Liver Diseases. Asian Journal of Nursing Education and Research. 2023;13(2):157–161. doi: 10.52711/2349-2996.2023.00034
  33. Cederholm T, Jensen GL, Correia MITD, Gonzalez MC, Fukushima R, Higashiguchi T, et al. GLIM criteria for the diagnosis of malnutrition – A consensus report from the global clinical nutrition community. Clinical Nutrition. 2019;38(1):1–9. doi: 10.1016/j.clnu.2018.08.002
  34. Stephenson GR, Moretti EW, El-Moalem H, Clavien PA, Tuttle-Newhall JE. Malnutrition in liver transplant patients. Pre operative subjective global assessment is predictive of outcome after liver transplantation. Transplantation. 2001;72(4):666–70.
  35. Figueiredo F, Dickson ER, Pasha T, Kasparova P, Therneau T, Malinchoc M, et al. IMPACT OF NUTRITIONAL STATUS ON OUTCOMES AFTER LIVER TRANSPLANTATION1. Transplantation. 2000;70(9):1347–1352. doi: 10.1097/00007890-200011150-00014
  36. Cuerda C, Pironi L, Arends J, Bozzetti F, Gillanders L, Jeppesen PB, et al. ESPEN practical guideline: Clinical nutrition in chronic intestinal failure. Clinical Nutrition. 2021;40(9):5196–5220. doi: 10.1016/j.clnu.2021.07.002
  37. Uchida H, Yamamoto H, Kisaki Y, Fujino J, Ishimaru Y, Ikeda H. D-lactic acidosis in short-bowel syndrome managed with antibiotics and probiotics. Journal of Pediatric Surgery. 2004;39(4):634–636. doi: 10.1016/j.jpedsurg.2003.12.026
  38. Weimann A, Braga M, Carli F, Higashiguchi T, Hübner M, Klek S, et al. ESPEN practical guideline: Clinical nutrition in surgery. Clinical Nutrition. 2021;40(7):4745–4761. doi: 10.1016/j.clnu.2021.03.031

Copyright

© This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Published By India Association for Parenteral and Enteral Nutrition (IAPEN)

  • 07 June 2024

Year: 2024, Volume: 12, Issue: 1


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