Journal of Nutrition Research
DOI: 10.55289/jnutres/v13i2.25.23
Year: 2025, Volume: 13, Issue: 2, Pages: 46-54
Original Article
D Swetha Sri1*, Haritha Bathina2, Sowmya V3
1Department of Clinical Nutrition and Dietetics, Apollo Hospitals, Jubilee Hills, Hyderabad, India.
2HOD, Department of Clinical Nutrition and Dietetics, Apollo Hospitals, Hyderabad, India.
3Department of Clinical Nutrition and Dietetics, Apollo Hospitals, Hyderabad, India
*Corresponding Author
Email: [email protected]
Received Date:06 May 2025, Accepted Date:22 November 2025, Published Date:18 December 2025
Background: In diabetic subjects, type of cereal used has an impact on glycemia and nutritional therapy can help in management of Glycemic status. Objectives: To determine the efficacy of Nutritional Councelling and Quinoa supplementation on postprandial blood sugars in diabetic subjects. Methods: Patients were randomly divided into two groups. The experimental group (n=10) received nutritional counselling and Quinoa (Raw-60g) based meal at lunch for 28 days. The control group (n=10) received only nutritional counselling and were not given any supplementation. Results: In the experimental group, 90% of subjects were males and 10% were females, while in the control group all subjects were males. 30% of the subjects in experimental group and 40% of control group belonged to age group of 30-39 years. In experimental group, there was a decrease in the postprandial blood sugars at the end of study period compared to the baseline (181.6 ± 82.5 to 136.7 ± 21.5 mg/dl) (p=0.09) however not significant. There was a statistically significant decrease in the intake of energy, carbohydrates and fats (p<0.05), with a non significant increase in protein intake (p=0.1). In the control group, there was a non-significant increase in the PPBS levels at the end of study period (217 ± 83.4 to 228.4 ± 101.1 mg/dl) (p=0.39).The control group subjects showed a statistically significant decrease in the intake of energy, carbohydrates, and fats (p<0.05) with a non-significant increase in the daily protein intake (p=0.17) at the end of study after nutritional counselling. The baseline PPBS (181.6mg/dl) levels statistically similar between the two groups, however, the PPBS levels at day10 (151mg/dl), day 20(149.9mg/dl) and end of study were significantly lower in experimental group as compared to the control group (p<0.05). However, the trends towards significantly lower energy and carbohydrate intake in the experimental group was present from the start of the study period (p<0.05). Conclusion: Glycemic variation is prevalent among diabetic subjects. Quinoa supplementation caused a significant decrease in PPBS levels and also improved the overall macronutrient intake. The study also shows the effect of nutritional counselling, as there was an improvement in the macro-nutrient intake status in the control as well.
Keywords: Quinoa; Benefits; Uses in managing diabetes; Diabetes mellitus; Post-prandial blood glucose; Functional foods; Glycemic control; Nutritional intervention
1. Wild S, Roglic G, Green A, Sicree R, King H. Global Prevalence of Diabetes. Diabetes Care. 2004; 27 (5). Available from: https://doi.org/10.2337/diacare.27.5.1047
2. World Health Organization. <I>Global Report on Diabetes</I>. Geneva, 2016. Accessed 31 March 2017.
3. Gale, J. <I>India’s Diabetes Epidemic Cuts Down Millions Who Escape Poverty</I>. (November 7, 2010). Bloomberg.
4. <I>China faces 'diabetes epidemic', research suggests</I>. BBC. March 25, 2010. Retrieved 8 June 2012.
5. <I>Diabetes can be controlled in 80 percent of Cases in India</I>. IANS. news.biharprabha.com. Retrieved 6 February 2014.
6. Indian Heart Association. <I>Why South Asians. Overview</I>. 30 April 2015. http://indianheartassociation.org/why-indians-why-south-asians/overview/
7. King H, Aubert RE, Herman WH. Global Burden of Diabetes, 1995–2025: Prevalence, numerical estimates, and projections. Diabetes Care. 1998; 21 (9). Available from: https://doi.org/10.2337/diacare.21.9.1414
8. <I>Diabetes Risk factors - Mayo Clinic</I>. Accessed March 31, 2017. Available at: http://www.mayoclinic.org/diseasesconditions/diabetes/basics/riskfactors/con20033091.
9. Buyken AE, von Eckardstein A, Schulte H, Cullen P, Assmann G. Type 2 diabetes mellitus and risk of coronary heart disease: results of the 10-year follow-up of the PROCAM study. European Journal of Cardiovascular Prevention & Rehabilitation. 2007; 14 (2). Available from: https://doi.org/10.1097/hjr.0b013e3280142037
10. Bonora E, Formentini G, Calcaterra F, Lombardi S, Marini F, Zenari L, <I>et al</I>. HOMA-Estimated Insulin Resistance Is an Independent Predictor of Cardiovascular Disease in Type 2 Diabetic Subjects. Diabetes Care. 2002; 25 (7). Available from: https://doi.org/10.2337/diacare.25.7.1135
11. Drummond K, Mauer M. The Early Natural History of Nephropathy in Type 1 Diabetes. Diabetes. 2002; 51 (5). Available from: https://doi.org/10.2337/diabetes.51.5.1580
12. Brenner BM, Cooper ME, de Zeeuw D, Keane WF, Mitch WE, Parving HH, <I>et al</I>. Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy. New England Journal of Medicine. 2001; 345 (12). Available from: https://doi.org/10.1056/nejmoa011161
13. World Health Organization. <I>Diabetes facts</I>. Accessed December 13, 2007. Available at: http://www.who.int/mediacentre/factsheets/fs312/en/index.html.
14. Dansinger M. <I>Best and Worst Food for Diabetes</I>. (2016). Available at: http://www. webmd.com/diabetes/diabetic-food-list-best-worst-foods
15. Jali MV, Kamatar MY, Jali SM, Hiremath MB, Naik RK. Efficacy of value added foxtail millet therapeutic food in the management of diabetes and dyslipidamea in type 2 diabetic patients. <I>Recent Research in Science and Technology</I> 2012, 4(7): 03-04.
16. Jenkins DJ, Wolever TM, Taylor RH, Griffiths C, Krzeminska K, Lawrie JA, <I>et al</I>. Slow release dietary carbohydrate improves second meal tolerance. The American Journal of Clinical Nutrition. 1982; 35 (6). Available from: https://doi.org/10.1093/ajcn/35.6.1339
17. Berti C, Riso P, Monti LD, Porrini M. In vitro starch digestibility and in vivo glucose response of gluten?free foods and their gluten counterparts. European Journal of Nutrition. 2004; 43 (4). Available from: https://doi.org/10.1007/s00394-004-0459-1
18. Mithila MV, Khanum F. Effectual comparison of quinoa and amaranth supplemented diets in controlling appetite; a biochemical study in rats. Journal of Food Science and Technology. 2015; 52 (10). Available from: https://doi.org/10.1007/s13197-014-1691-1
19. Graf BL, Rojas-Silva, P, Rojo LE, Delatorre-Herrera J, Baldeón ME, Raskin I. Innovations in Health Value and Functional Food Development of Quinoa ( <i>Chenopodium quinoa</i> Willd.). Comprehensive Reviews in Food Science and Food Safety. 2015; 14 (4). Available from: https://doi.org/10.1111/1541-4337.12135
20. Mirmiran P, Bahadoran Z, Azizi F. Functional foods-based diet as a novel dietary approach for management of type 2 diabetes and its complications: A review. World Journal of Diabetes. 2014; 5 (3). Available from: https://doi.org/10.4239/wjd.v5.i3.267
21. Abugoch James LE. Quinoa (<I>Chenopodium quinoa</I> Willd.): Composition, chemistry, nutritional and functional properties. Advances in Food and Nutrition Research. 2009; Available from: https://doi.org/10.1016/s1043-4526(09)58001-1
22. Gabrial SGN, Shakib M-CR, Gabrial GN. Effect of Pseudocereal-Based Breakfast Meals on the First and Second Meal Glucose Tolerance in Healthy and Diabetic Subjects. Open Access Macedonian Journal of Medical Sciences. 2016; 4 (4). Available from: https://doi.org/10.3889/oamjms.2016.115
© This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Published By India Association for Parenteral and Enteral Nutrition (IAPEN)
Subscribe now for latest articles and news.