Journal of Nutrition Research
DOI: 10.55289/jnutres/v13i2.25.72
Year: 2025, Volume: 13, Issue: 2, Pages: 59-65
Original Article
Deepashri Chinya Venkatesh1, Hemalatha Mysore Sreekantaiah1*
1DOS&R in Food Science and Nutrition, Karnataka State Open University, Mukthagangothri, Mysore - 570 006, Karnataka, India
*Corresponding Author
Email: [email protected]
Received Date:29 July 2025, Accepted Date:16 December 2025, Published Date:24 December 2025
Aim: The aim of this study was to show the effect of a 12-week nutritional counselling intervention on biochemical indicators, i.e., glycosylated haemoglobin (HbA1c), in prediabetic users and fasting blood glucose (FBS). Materials: A total of 499 pre-diabetic subjects (aged 20–60 years) were included in this prospective interventional study. Subjects were divided into an intervention group (n=309) who received a 12-week structured nutritional counselling program with controlled dietary advice emphasizing low-glycaemic-index food consumption, increased fibre intake, macronutrient redistribution, and exercise (150 minutes/week) and a control group (n=190) who did not engage, failing to initiate or sustain participation in the structured program. Biochemistry tests were performed pre- and post-intervention. Results: A significant alterations in HbA1c and FBS in all age groups spanning both genders. Although the 40–50 years group showed maximum FBS reduction (8.4 mg/dL), the 20–30 years age group showed optimal HbA1c reduction in men (0.3%). In women, optimal HbA1c reductions were seen in the 30–40 years group (0.2%) and in postmenopausal women (50–60 years) changed very little, perhaps in line with hormonal influences. Women, particularly premenopausal, showed clearly higher HbA1c reductions compared to men. Conclusion: Younger subjects' optimal glycaemic control can be explained by greater metabolic flexibility and adherence to lifestyle.
Keywords: Prediabetes, Nutritional counselling, HbA1c, Fasting blood sugar, Lifestyle intervention, Gender differences
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Published By India Association for Parenteral and Enteral Nutrition (IAPEN)
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