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Journal of Nutrition Research
An official journal of IAPEN India association

Article

A Panel Discussion in Nutritional Management in Cancer Care
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Journal of Nutrition Research

DOI: 10.55289/jnutres/v11i1_23.1

Year: 2023, Volume: 11, Issue: 1, Pages: 28-32

Review Article

A Panel Discussion in Nutritional Management in Cancer Care

Shivshankar Timmanpyati 1 , B Ravinder Reddy 2 , Sunitha Premalatha 3 , A Rajeswari 4 , Prasanthi Suryanaryana 5 , Sai Sankalp Naidu 6 , Bhakti Samant​✉ 7

1 Tata Memorial Hospital (HBNI), Mumbai, India
2 Care Hospitals, Hyderabad, India
3 Yashoda Hospitals, Mumbai, India
4 Apollo Hospitals, Hyderabad, India
5 Indo American Hospital, Hyderabad, India
6 Bibi Cancer Hospital, Hyderabad, India
7 Kokilaben Dhirubhai Ambani Hospital, Mumbai, India

Corresponding author ✉ : [email protected]

Received Date:24 January 2023, Accepted Date:28 January 2023, Published Date:30 January 2023

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Nutritional status plays an important role in cancer treatment. Several studies have strongly indicated that malnutrition has a negative impact on the efficacy of cancer treatment. Nutritional negligence or poor nutrition may impede the progress in cancer care, rendering them a harder time with the toxic side effects. It is well documented that there is a high prevalence of cancer-related malnutrition ranging from 25% to 70% from various studies, and cancer patients are the most malnourished of all other patient groups. Escalation of nutrients, effective counseling, and consistent monitoring as an adjuvant to cancer treatment, not only improve nutrition parameters, and body composition but also help in managing toxic effects, thus enhancing the quality of life and ultimately better survival.

 

Keywords: Cancer nutrition, Onconutrition, Malnutrition

References

  1. Fearon K, Barber M, Moses A. The cancer cachexia syndrome. Surg Oncol Clin N Am. 2001;10(1):109–126. Available from: https://pubmed.ncbi.nlm.nih.gov/11406454/
  2. Mattox TW. Cancer Cachexia: Cause, Diagnosis, and Treatment. Nutrition in Clinical Practice. 2017;32(5):599–606. Available from: https://doi.org/10.1177/0884533617722986
  3. Wys WDD, Begg C, Lavin PT, Band PR, Bennett JM, Bertino JR, et al. Prognostic effect of weight loss prior to chemotherapy in cancer patients. Am J Med. 1980;69(4):491–497. Available from: https://doi.org/10.1016/s0149-2918(05)80001-3
  4. Wigmore SJ, Plester CE, Ross JA, Fearon KCH. Contribution of anorexia and hypermetabolism to weight loss in anicteric patients with pancreatic cancer. British Journal of Surgery. 1997;84(2):196–197. Available from: https://pubmed.ncbi.nlm.nih.gov/9052431/
  5. Belghiti J, Langonnet F, Bourstyn E, Fekete F. Surgical implications of malnutrition and immunodeficiency in patients with carcinoma of the oesophagus. British Journal of Surgery. 2005;70(6):339–341. Available from: https://doi.org/10.1002/bjs.1800700610
  6. Mantzorou M, Koutelidakis A, Theocharis S, Giaginis C. Clinical Value of Nutritional Status in Cancer: What is its Impact and how it Affects Disease Progression and Prognosis? Nutrition and Cancer. 2017;69(8):1151–1176. Available from: https://doi.org/10.1080/01635581.2017.1367947
  7. Ravasco P, Monteiro-Grillo I, Vidal PM, Camilo ME. Nutritional Deterioration in Cancer: The Role of Disease and Diet. Clinical Oncology. 2003;15(8):443–450. Available from: https://doi.org/10.1016/s0936-6555(03)00155-9
  8. Prado CM, Cushen SJ, Orsso CE, Ryan AM. Sarcopenia and cachexia in the era of obesity: clinical and nutritional impact. Proceedings of the Nutrition Society. 2016;75(2):188–198. Available from: https://doi.org/10.1017/s0029665115004279
  9. Bazzan AJ, Newberg AB, Cho WC, Monti DA. Diet and Nutrition in Cancer Survivorship and Palliative Care. Evidence-Based Complementary and Alternative Medicine. 2013;2013:1–12. Available from: https://doi.org/10.1155/2013/917647
  10. Orell-Kotikangas H, Österlund P, Mäkitie O, Saarilahti K, Ravasco P, Schwab U, et al. Cachexia at diagnosis is associated with poor survival in head and neck cancer patients. Acta Oto-Laryngologica. 2017;137(7):778–785. Available from: https://doi.org/10.1080/00016489.2016.1277263
  11. Fearon K, Strasser F, Anker SD, Bosaeus I, Bruera E, Fainsinger RL, et al. Definition and classification of cancer cachexia: an international consensus. The Lancet Oncology. 2011;12(5):489–495. Available from: https://doi.org/10.1016/s1470-2045(10)70218-7
  12. Donaldson S. Nutritional consequences of radiotherapy. Cancer Res. 1997;37(7 pt 2):2407–2413. Available from: https://pubmed.ncbi.nlm.nih.gov/861954/
  13. Blauwhoff-Buskermolen S, Versteeg KS, Schueren MAEDVD, Braver NRD, Berkhof J, Langius JAE, et al. Loss of Muscle Mass During Chemotherapy Is Predictive for Poor Survival of Patients With Metastatic Colorectal Cancer. Journal of Clinical Oncology. 2016;34(12):1339–1344. Available from: https://doi.org/10.1200/jco.2015.63.6043
  15. Weimann A, Braga M, Carli F, Higashiguchi T, Hübner M, Klek S, et al. ESPEN guideline: Clinical nutrition in surgery. Clinical Nutrition. 2017;36(3):623–650. Available from: https://doi.org/10.1016/j.clnu.2017.02.013
  16. Arends J, Bachmann P, Baracos V, Barthelemy N, Bertz H, Bozzetti F, et al. ESPEN guidelines on nutrition in cancer patients. Clinical Nutrition. 2017;36(1):11–48. Available from: https://doi.org/10.1016/j.clnu.2016.07.015
  17. Arends J, Baracos V, Bertz H, Bozzetti F, Calder PC, Deutz NEP, et al. ESPEN expert group recommendations for action against cancer-related malnutrition. Clinical Nutrition. 2017;36(5):1187–1196. Available from: https://doi.org/10.1016/j.clnu.2017.06.017
  18. Benoist S, Brouquet A. Nutritional assessment and screening for malnutrition. Journal of Visceral Surgery. 2015;152(S1):S3–S7. Available from: https://doi.org/10.1016/s1878-7886(15)30003-5
  19. Peñas RDL, Majem M, Perez-Altozano J, Virizuela JA, Cancer E, Diz P, et al. SEOM clinical guidelines on nutrition in cancer patients (2018) Clinical and Translational Oncology. 2019;21(1):87–93. Available from: https://doi.org/10.1007/s12094-018-02009-3
  21. Thompson KL, Elliott L, Fuchs-Tarlovsky V, Levin RM, Voss AC, Piemonte T. Oncology Evidence-Based Nutrition Practice Guideline for Adults. Journal of the Academy of Nutrition and Dietetics. 2017;117(2):297–310.e47. Available from: https://doi.org/10.1016/j.jand.2016.05.010
  22. Talwar B, Donnelly R, Skelly R, Donaldson M. Nutritional management in head and neck cancer: United Kingdom National Multidisciplinary Guidelines. The Journal of Laryngology & Otology. 2016;130(S2):S32–S40. Available from: https://doi.org/10.1017%2FS0022215116000402
  23. Orell-Kotikangas H, Österlund P, Saarilahti K, Ravasco P, Schwab U, Mäkitie AA. NRS-2002 for pre-treatment nutritional risk screening and nutritional status assessment in head and neck cancer patients. Supportive Care in Cancer. 2015;23(6):1495–1502. Available from: https://doi.org/10.1007/s00520-014-2500-0
  24. CBT, Monteiro-Grillo I, Camilo M, Ravasco P. Validation of the Malnutrition Universal Screening Tool (MUST) in cancer. Br J Nutr. 2012;108(2):343–348. Available from: https://doi.org/10.1017/s000711451100571x
  25. Boléo-Tomé C, Chaves M, Monteiro-Grillo I, Camilo M, Ravasco P. Teaching Nutrition Integration: MUST Screening in Cancer. Oncologist. 2011;16(2):239–245. Available from: https://doi.org/10.1634/theoncologist.2010-0203
  27. Staun M, Pironi L, Bozzetti F, Baxter J, Forbes A, Joly F, et al. ESPEN Guidelines on Parenteral Nutrition: Home Parenteral Nutrition (HPN) in adult patients. Clinical Nutrition. 2009;28(4):467–479. Available from: https://doi.org/10.1016/j.clnu.2009.04.001
  28. Souza NCS, Simões BP, Júnior AAJ, Chiarello PG. Changes in Intestinal Permeability and Nutritional Status After Cytotoxic Therapy in Patients with Cancer. Nutrition and Cancer. 2014;66(4):576–582. Available from: https://doi.org/10.1080/01635581.2014.894095
  29. Raspé C, Flöther L, Schneider R, Bucher M, Piso P. Best practice for perioperative management of patients with cytoreductive surgery and HIPEC. Eur J Surg Oncol. 2017;43(6):1013–1027. Available from: https://doi.org/10.1016/j.ejso.2016.09.008
  30. O’reilly D, Fou L, Hasler E, Hawkins J, SO, Pelone F, et al. Diagnosis and management of pancreatic cancer in adults: A summary of guidelines from the UK National Institute for Health and Care Excellence. Pancreatology. 2018;18(8):962–970. Available from: https://doi.org/10.1016/j.pan.2018.09.012
  31. Lis CG, Gupta D, Lammersfeld CA, Markman M, Vashi PG. Role of nutritional status in predicting quality of life outcomes in cancer – a systematic review of the epidemiological literature. Nutrition Journal. 2012;11(1):27. Available from: https://doi.org/10.1186/1475-2891-11-27
  33. Obermair A, Simunovic M, Isenring L, Janda M. Nutrition interventions in patients with gynecological cancers requiring surgery. Gynecologic Oncology. 2017;145(1):192–199. Available from: https://doi.org/10.1016/j.ygyno.2017.01.028
  35. Deutz NEP, Safar A, Schutzler S, Memelink R, Ferrando A, Spencer H, et al. Muscle protein synthesis in cancer patients can be stimulated with a specially formulated medical food. Clinical Nutrition. 2011;30(6):759–768. Available from: https://doi.org/10.1016/j.clnu.2011.05.008
  36. Shachar SS, Williams GR, Muss HB, Nishijima TF. Prognostic value of sarcopenia in adults with solid tumours: A meta-analysis and systematic review. European Journal of Cancer. 2016;57:58–67. Available from: https://doi.org/10.1016/j.ejca.2015.12.030
  37. Shachar SS, Deal AM, Weinberg M, Nyrop KA, Williams GR, Nishijima TF, et al. Skeletal Muscle Measures as Predictors of Toxicity, Hospitalization, and Survival in Patients with Metastatic Breast Cancer Receiving Taxane-Based Chemotherapy. Clinical Cancer Research. 2017;23(3):658–665. Available from: https://doi.org/10.1158/1078-0432.ccr-16-0940
  38. Ray-Coquard I, Cropet C, Glabbeke MV, Sebban C, Cesne AL, Judson I, et al. Lymphopenia as a Prognostic Factor for Overall Survival in Advanced Carcinomas, Sarcomas, and Lymphomas. Cancer Research. 2009;69(13):5383–5391. Available from: https://doi.org/10.1158/0008-5472.can-08-3845
  39. Tozer RG, Tai P, Falconer W, Ducruet T, Karabadjian A, Bounous G, et al. Cysteine-Rich Protein Reverses Weight Loss in Lung Cancer Patients Receiving Chemotherapy or Radiotherapy. Antioxidants & Redox Signaling. 2008;10(2):395–402. Available from: https://doi.org/10.1089/ars.2007.1919
  40. Gillis C, Loiselle SEE, Fiore JF, Awasthi R, Wykes L, Liberman AS, et al. Prehabilitation with Whey Protein Supplementation on Perioperative Functional Exercise Capacity in Patients Undergoing Colorectal Resection for Cancer: A Pilot Double-Blinded Randomized Placebo-Controlled Trial. Journal of the Academy of Nutrition and Dietetics. 2016;116(5):802–812. Available from: https://doi.org/10.1016/j.jand.2015.06.007
  41. Bumrungpert A, Pavadhgul P, Nunthanawanich P, Sirikanchanarod A, Adulbhan A. Whey Protein Supplementation Improves Nutritional Status, Glutathione Levels, and Immune Function in Cancer Patients: A Randomized, Double-Blind Controlled Trial. Journal of Medicinal Food. 2018;21(6):612–616. Available from: https://doi.org/10.1089/jmf.2017.4080
  42. Devries MC, Phillips SM. Supplemental Protein in Support of Muscle Mass and Health: Advantage Whey. Journal of Food Science. 2015;80(S1):A8–A15. Available from: https://doi.org/10.1111/1750-3841.12802
  43. Bauer JM, Verlaan S, Bautmans I, Brandt K, Donini LM, Maggio M, et al. Effects of a Vitamin D and Leucine-Enriched Whey Protein Nutritional Supplement on Measures of Sarcopenia in Older Adults, the PROVIDE Study: A Randomized, Double-Blind, Placebo-Controlled Trial. Journal of the American Medical Directors Association. 2015;16(9):740–747. Available from: https://doi.org/10.1016/j.jamda.2015.05.021
  44. Rondanelli M, Klersy C, Terracol G, Talluri J, Maugeri R, Guido D, et al. Whey protein, amino acids, and vitamin D supplementation with physical activity increases fat-free mass and strength, functionality, and quality of life and decreases inflammation in sarcopenic elderly. The American Journal of Clinical Nutrition. 2016;103(3):830–840. Available from: https://doi.org/10.3945/ajcn.115.113357
  46. Freitas R, Campos MM. Protective Effects of Omega-3 Fatty Acids in Cancer-Related Complications. Nutrients. 2019;11(5):945. Available from: https://doi.org/10.3390/nu11050945
  47. Papallardo G, Almeida A, Ravasco P. Eicosapentaenoic acid in cancer: Does it improve body composition and modulate metabolism? Nutrition. 2015;31(4):549–555. Available from: https://doi.org/10.1016/j.nut.2014.12.002
  48. Lavriv DS, Neves PM, PR. Should omega-3 be used in cancer cachexia? Clin Nutr ESPEN. 2018;25:18–25. Available from: https://doi.org/10.1016/j.clnesp.2018.02.006
  49. Hering J, Garrean S, Dekoj TR, Razzak A, Saied A, Trevino J, et al. Inhibition of Proliferation by Omega-3 Fatty Acids in Chemoresistant Pancreatic Cancer Cells. Annals of Surgical Oncology. 2007;14(12):3620–3628. Available from: https://doi.org/10.1245/s10434-007-9556-8
  50. Murphy RA, Mourtzakis M, Mazurak VC. n-3 polyunsaturated fatty acids: The potential role for supplementation in cancer. Curr Opin Clin Nutr Metab Care. 2012;15:246–251.

Copyright

© This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Published By India Association for Parenteral and Enteral Nutrition (IAPEN)

  • 03 February 2023

Year: 2023, Volume: 11, Issue: 1


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